From the point of view manufacturer, machine tools fulfill technological requirements of manufacturing processes for part geometrical dimensions, shaping, and material property change. Main machine tool functions are axis motions with sufficient power reserve drives to technological process loads, consuming energy. The participation of manufacturing systems and processes for sustainable life in industrial applications and limiting earth warming up is required. This paper is responding to a scientific demand in setting development trends for manufacturing systems, processes and the environment. Here a scientific question arises: which technological requirements and machine functionalities to machine tool characteristics lead to their lowest resource consumption/losses and part manufacturing costs? The machine tool manufacturer methodology is following a relation and dependency analysis, combined with functional synthesis and resource optimization. The machine tool user applies the key performance indicator “Overall Equipment Effectiveness OEE” integrates efficiency values for productivity, availability, quality, targeting minimal part manufacturing costs.